Isopropyl Myristate CAS 110-27-0 | Cosmetic Grade IPM

• Isopropyl Myristate (INCI: Isopropyl Myristate, industry abbreviation IPM, CAS 110-27-0) is a low-viscosity fatty acid ester produced via esterification of natural myristic acid and isopropyl alcohol. It appears as a colorless, transparent, nearly odorless oily liquid.
  
  
• As one of the most widely used synthetic ester oil raw materials in the cosmetic industry, it features exceptional skin permeability, a lightweight non-greasy skin feel, and excellent solubilizing and thickening properties.
  
  
• It serves as a multifunctional cosmetic ingredient with combined roles of emollient, solubilizer, skin penetration enhancer and thickener, extensively applied in skincare products, color cosmetics, hair care, sun care formulations, perfumes and topical pharmaceutical preparations.
  
  
• As a direct source manufacturer, we supply high-purity isopropyl myristate in both cosmetic grade and pharmaceutical excipient grade, with guaranteed stable bulk supply capacity.

1. Direct Source Factory Supply

Backed by our in-house esterification production lines, we use natural myristic acid derived from coconut oil / palm kernel oil as raw material, ensuring stable fulfillment for large bulk orders and offering highly competitive ex-factory prices.

2. Superior Skin Feel & Absorption Performance

Features a lightweight non-oily texture, excellent spreadability, and fast non-sticky skin penetration, being rapidly absorbed by the skin without greasy residue.

3. Integrated Multifunctional Properties

Combines multiple functions of emollient, penetration enhancer, solubilizer, thickener and lubricant in one ingredient, effectively simplifying formulation design for R&D teams.

4. High Purity & Global Regulatory Compliance

Available in high-purity specification of ≥99.5%, fully compliant with USP/NF, EP pharmacopoeia standards and global cosmetic regulatory requirements.

5. Excellent Formulation Compatibility

Highly compatible with all types of surfactants and functional active ingredients for cosmetic and topical pharmaceutical formulations.

 1. Skincare & Personal Care (Core Application)

Isopropyl Myristate is a signature ingredient for mid-to-high end skincare products, with a recommended dosage of 2% – 10% in formulations.

Moisturizers, lotions & body lotions: Delivers a lightweight skin feel, fast penetration, improves skin softness and smoothness without greasy residue

Sun care products: Acts as a solvent to disperse UV filters, enhances product skin feel and spreadability

Makeup removers & cleansing creams: Gently dissolves makeup and surface impurities with its excellent oil-dissolving capacity

Bath oils & body oils: As a non-oily emollient ester, it does not form an oily film, delivers a smooth skin touch with excellent re-fatting performance

Shaving creams & hair conditioners: Lubricates skin and reduces irritation

Safety profile: Evaluated as safe for cosmetic use by CIR Expert Panel, with a safety risk score of 1-2

2. Color Cosmetics & Hair Care

Lipsticks, lip balms & liquid foundations: Acts as a binder, improves powder dispersion and skin adhesion, delivers excellent spreadability

Pressed powder cosmetics: Serves as a lubricant and compression aid for pressed powders, supporting powder molding

Perfumes & fragrances: Functions as a fixative to extend fragrance longevity

Hair conditioners & styling gels: Imparts hair gloss, improves combability and reduces frizz

3. Pharmaceutical & Medicinal Excipients

Transdermal drug delivery systems: As a pharmaceutical excipient for ointments, creams and topical formulations, it significantly enhances drug permeability and bioavailability

Pharmaceutical solvent & carrier: Serves as a component of semi-solid bases, solubilizes a wide range of active pharmaceutical ingredients

4. Food & Flavor Industry

Food flavoring agent: Approved as a synthetic food flavor with FEMA No. 3556, permitted for use in all food categories at appropriate levels per production requirements

Q1: What is Isopropyl Myristate, and what is its standard identifier?

A: Isopropyl Myristate (INCI: Isopropyl Myristate, industry abbreviation IPM, CAS 110-27-0, alias Isopropyl Tetradecanoate) is a low-viscosity synthetic fatty acid ester produced via esterification of natural myristic acid (derived from coconut oil/palm kernel oil) and isopropyl alcohol. It appears as a colorless, nearly odorless transparent oily liquid, and is one of the most widely used emollient ester raw materials in the global cosmetic industry.

Q2: What core functions does Isopropyl Myristate serve in formulations?

A: IPM is a multifunctional raw material with 5 core roles:

Emollient: Delivers soft, smooth skin feel without greasy residue

Penetration enhancer: Improves skin absorption of active ingredients

Solubilizer: Dissolves UV filters, active ingredients and fragrance components

Thickener & binder: Improves formulation consistency and powder adhesion in cosmetics

Lubricant: Reduces friction and improves spreadability of products

Q3: What is the recommended usage level of Isopropyl Myristate?

A: The standard recommended dosage of Isopropyl Myristate is 2% – 10% for most cosmetic and personal care formulations. Dosage can be adjusted according to product type: 2-5% for lightweight lotions, 5-10% for creams, sunscreens and makeup products, and adjusted accordingly for pharmaceutical preparations based on formulation requirements.

Q4: In which products is Isopropyl Myristate commonly applied?

A: As a highly versatile ester raw material, IPM is widely used across 4 major industries:

Cosmetics & personal care: Creams, lotions, sunscreens, makeup removers, body oils, shaving products and baby care

Color cosmetics: Lipsticks, liquid foundations, pressed powders and perfumes (as a fixative)

Pharmaceuticals: Topical ointments, creams and transdermal drug delivery systems (as an absorption enhancer)

Food & flavor: Approved food flavoring agent (FEMA No. 3556)

Q5: Why is IPM widely used in mid-to-high end skincare products?

A: Isopropyl Myristate is preferred for premium formulations for three core advantages:

Superior skin feel: Lightweight non-greasy texture, fast penetration, no sticky residue or oily film on skin

Excellent spreadability: Evenly spreads on skin without white cast or heavy feeling

Stable performance: Maintains stable properties across a wide pH range, compatible with most formulation systems

Q6: Is Isopropyl Myristate compliant with global regulatory standards?

A: Yes, IPM is a globally approved raw material:

Cosmetic use: Evaluated as safe by CIR Expert Panel (safety risk score 1-2), compliant with EU and China cosmetic regulations

Pharmaceutical use: Meets USP/NF, EP pharmacopoeia standards for pharmaceutical excipients

Food use: Approved as a synthetic food flavor with FEMA No. 3556, permitted for use in all food categories

Q7: Is Isopropyl Myristate compatible with common cosmetic ingredients?

A: Yes, IPM has excellent formulation compatibility. It works stably with anionic, cationic and nonionic surfactants, UV filters, plant extracts, proteins and most functional active ingredients, and will not affect the efficacy of other components in formulations.

Q8: What are the key quality specifications for cosmetic-grade IPM?

A: Premium cosmetic and pharmaceutical grade Isopropyl Myristate meets the following core specifications:

Purity (GC): ≥98.0% – 99.5%

Specific gravity (20°C): 0.850 – 0.860 g/mL

Acid value: ≤1.0 mg KOH/g

Refractive index (20°C): 1.432 – 1.438

Flash point: 152°C

Moisture: ≤1.0%

Q9: Is Isopropyl Myristate safe for sensitive skin and baby care products?

A: Yes. Isopropyl Myristate has a very low irritation risk profile, with a CIR safety risk score of 1-2 (lowest risk tier). When used within the recommended dosage of 2%-10%, it is considered safe for sensitive skin and baby care formulations, and is widely used in infant lotions and gentle skincare products.

Q10: What role does IPM play in pharmaceutical preparations?

A: As a pharmaceutical excipient, Isopropyl Myristate is mainly used in topical and transdermal formulations:

It significantly enhances the skin permeability of active pharmaceutical ingredients, improving drug bioavailability

It serves as a solvent and carrier for semi-solid bases, dissolving a wide range of active components

It improves the spreadability and skin feel of ointments and creams

Q11: What packaging and supply services do you provide?

A: As a direct source manufacturer, we supply cosmetic-grade and pharmaceutical-grade IPM with purity up to 99.5%. Standard packaging options include 25kg drums, 200kg drums and 1000L IBC totes, with customizable packaging available. We support stable bulk supply from lab samples to full container orders, and provide complete regulatory documentation including COA, MSDS/SDS and TDS for each batch.