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Item No :
ArbutinOrder(MOQ) :
100kgsProduct Origin :
ChinaColor :
White to off-whiteShipping Port :
Shanghai, ChinaLead Time :
2-3 weeksWeight :
25kgCas No. :
- β-Arbutin: 497-76-7 - α-Arbutin: 84380-01-8Molecular Formula :
C₁₂H₁₆O₇Appearance :
White needle-shaped crystals or free-flowing powder, odorless, uniform texture with no visible impuritiesAssay :
- β-Arbutin: ≥ 98% – 99% (HPLC) - α-Arbutin: ≥ 99% (HPLC)Application :
Skincare Hair Care Pharmaceuticals
Arbutin (CAS 497-76-7) is a naturally occurring glycosylated hydroquinone derivative, mainly extracted from the leaves of plants such as bearberry and blueberry.
As a globally recognized potent tyrosinase inhibitor, arbutin blocks melanin production at the source by competitively inhibiting tyrosinase activity, providing multiple effects including skin brightening, spot fading, anti-oxidation and anti-inflammatory repair.
Compared with hydroquinone, arbutin is milder and less toxic, and can achieve obvious skin whitening effects at non-cytotoxic concentrations.
This product is widely used in high-end skincare products, pharmaceutical preparations and hair care products.
As a professional source manufacturer, we supply high-purity α-Arbutin and β-Arbutin, and support stable bulk supply for global industrial customers.
Core Advantages
Large‑scale Supply & Cost Advantages
As a professional source manufacturer of Arbutin, we rely on dual technical routes: plant extraction and synthetic biology. We ensure stable delivery for large bulk orders and provide highly competitive factory prices for global customers.
Strict Quality Control & Global Compliance
Our products comply with China’s Inventory of Cosmetic Ingredients Already Used, US FDA regulations and EU cosmetic standards.
A complete Certificate of Analysis (COA) is provided for every batch, covering HPLC purity, heavy metals, microbiological limits and other key safety indicators.
Multiple Specifications & Professional Technical Support
Product Types: β‑Arbutin, α‑Arbutin
Purity Grades: 98%, 99% and other customizable specifications
Application Support: We provide professional formulation advice for different scenarios, including stability in whitening serums and compatibility in acne‑fighting formulations.
Advanced Production Technology
β‑Arbutin: Produced via high‑quality plant extraction process.
α‑Arbutin: Manufactured using green bio‑synthesis technology with high added value, helping customers achieve differentiated market competition.
International Certifications & Export Support
Our Arbutin products are widely exported to North America, the European Union, Southeast Asia and other regions. We can provide full regulatory documents to meet the requirements of target markets worldwide.
Safety & Usage Guidelines
Safe Concentration: Arbutin is mild and safe at concentrations below 10%. Skin irritation may occur above 15%.
Sun Protection Advice: Daily sun protection is recommended during use, as high‑concentration arbutin may decompose under long‑term UV exposure.
Sensitivity Test: A patch test behind the ear is recommended for first‑time users.
Contraindications: Some users may be intolerant to arbutin, with possible redness, itching or stinging.
Formulation Compatibility:
Combined with niacinamide: improves skin brightness and barrier function.
Combined with vitamin C: provides synergistic whitening effects, but concentration control is required.
Storage: Keep sealed in a cool, dry place away from light.
Technical Specifications
| Item | β-Arbutin | α-Arbutin |
| CAS No. | 497-76-7 | 84380-01-8 |
| Molecular Formula | C₁₂H₁₆O | C₁₂H₁₆O₇ |
| Molecular Weight | 272.25 | 272.25 |
| Appearance | White needle-shaped crystals or powde | White needle-shaped crystals or powder |
| Purity (HPLC) | ≥ 98% – 99% | ≥ 99% |
| Melting Point | 195°C – 198°C | —— |
| Specific Optical Rotation | -64° (c=3) | —— |
| Solubility | Soluble in water and ethanol | Soluble in water and ethanol |
| Plant Source |
Extracted from bearberry leaves, blueberry, cowberry, etc. |
Produced via synthetic biotechnology |
| Core Characteristics |
Competitive tyrosinase inhibitor; Kiapp = 1.42 mM (monophenolase); 0.9 mM (diphenolase) |
Whitening effect is ~10 times that of β-Arbutin, with superior stability |
FAQ ：Arbutin
1. What is Arbutin?
Arbutin is a natural glycosylated hydroquinone derivative, mainly derived from bearberry leaves. It is a well‑known, safe and effective skin‑whitening ingredient that inhibits melanin production by suppressing tyrosinase activity.
2. What is the difference between α‑Arbutin and β‑Arbutin?
α‑Arbutin: more stable, better skin penetration, stronger whitening effect (about 8–10 times that of β‑Arbutin).
β‑Arbutin: mainly from plant extraction, cost-effective, widely used in daily skincare products.
3. How does Arbutin whiten skin?
Arbutin blocks melanin synthesis at the source by competitively inhibiting tyrosinase, without damaging melanocytes. It effectively fades freckles, chloasma, age spots and post‑inflammatory hyperpigmentation.
4. Is Arbutin safe for skin?
Yes. Arbutin is milder, lower toxicity and less irritating than hydroquinone.
It is safe for most skin types at a concentration below 10%. Concentrations above 15% may cause skin irritation.
5. What is the recommended usage rate in cosmetics?
For whitening serums, creams and lotions: 1% – 5% is the most common and effective dosage.
6. Can Arbutin be used during the daytime?
Yes, but sun protection is highly recommended.
High‑concentration arbutin may decompose under long‑term UV exposure, affecting its stability and efficacy.
7. What ingredients can Arbutin pair with?
With niacinamide: enhance brightening and skin barrier repair.
With vitamin C: achieve synergistic whitening, but pay attention to pH and concentration control.
Not recommended to use with strong irritant exfoliants at the same time.
8. What products is Arbutin used in?
Skincare: whitening serums, spot‑correcting creams, after‑peeling repair products, acne creams.
Hair care: shampoos, conditioners (anti‑dandruff, soothe scalp).
Pharmaceuticals: diuretics, depigmenting agents, wound repair.
9. How to store Arbutin powder?
Keep in a sealed, cool, dry and dark place, avoid direct sunlight and high temperature.
Proper storage ensures high stability and long shelf life.
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