Allantoin (CAS 97-59-6) Cosmetic Grade – Bulk Supply for Skincare Formulations

• Large‑scale Supply & Cost Advantages
  As a professional source manufacturer of Allantoin, we rely on mature chemical synthesis technologies (including direct condensation of urea and glyoxylic acid) to ensure stable delivery for large bulk orders, and provide highly competitive factory prices for global industrial customers.
  
  
• Strict Quality Control & Global Compliance
  Our Allantoin fully complies with international standards such as USP23 and Chinese Pharmacopoeia.
  A complete Certificate of Analysis (COA) is provided for every batch, covering key quality and safety indicators including assay, loss on drying, residue on ignition, heavy metals and other critical testing items.
  
  
• Multiple Specifications & Professional Technical Support
  Assay Specifications: A variety of grades available, including ≥98% and ≥99% purity.
  Application Support: We provide professional formulation optimization suggestions for different scenarios, such as pharmaceutical preparations, cosmetic system stability, and agricultural formulation development.
  Stability Assurance: Allantoin is stable in dry air; its shelf life can reach 2–3 years when stored sealed, cool and away from light. It remains stable in aqueous solutions at pH 4–9, making it compatible with most formulation systems.
  
  
• International Certifications & Export Support
  Our Allantoin is widely exported to North America, the European Union, Southeast Asia and other regions. We can provide complete regulatory and customs documents to meet the requirements of target markets worldwide.
  
  
• Safety & Usage Guidelines
  Safety Profile: Allantoin is non-toxic, non-irritating and non-allergenic. It shows little skin irritation and rare allergic reactions, with no obvious contraindications for pregnant women and children. Products containing 0.5%–2% Allantoin are safe for daily use.
  Precautions: Avoid contact with eyes when used externally. A skin patch test is recommended for sensitive skin before use.
  Incompatibility Notes: Concomitant use with strong exfoliants (such as salicylic acid, alpha hydroxy acids) may cause excessive skin irritation. Concurrent use with tretinoin and other potent exfoliants may increase irritation risk; separate application is advised.
  Formulation Limitations: Allantoin is slightly soluble in water and has poor compatibility with some ingredients. It may crystallize in cream formulations, so process optimization is required in formulation development.

1. Pharmaceutical Industry: Wound Healing & Anti-Ulcer Agents

Allantoin exhibits physiological functions including promoting cell growth, accelerating wound healing, and softening keratin, making it an excellent skin wound healing agent and anti-ulcer medication.

Topical Preparations: Used to treat dry skin, cracked hands and feet, ichthyosis, senile pruritus, skin ulcers, wounds, acne, and chilblains. It enhances the hygroscopic capacity of keratinocytes, softens keratin, and leaves skin smooth and supple.

Oral Preparations: Administered for gastritis, gastric and duodenal ulcers at a dosage of 30–120 mg per dose, three times daily.

Scar Treatment: Formulated with heparin sodium and onion extract for the management of hypertrophic scars and keloids, promoting wound healing and relieving itching.

2. Cosmetics & Personal Care: High-Efficiency Moisturizing & Repair Additive

As an amphoteric compound, allantoin forms double salts with various substances, offering light protection, antiseptic, analgesic, and antioxidant properties.

Moisture Retention: Boosts the hydration ability of the stratum corneum, reduces transepidermal water loss, and provides strong moisturization for cracked and rough skin. 0.2% allantoin matches the efficacy of 10–20% urea without irritation.

Keratin Softening: Directly acts on keratin to enhance water binding, loosening and exfoliating scales for smooth, flexible skin.

Tissue Repair: Stimulates cell proliferation, accelerates metabolism, and promotes epithelial regeneration.

Soothing & Anti-Irritation: Provides mild analgesic, anesthetic, and anti-irritant effects, neutralizing irritants and calming skin.

Product Applications: Widely used in freckle creams, acne lotions, shampoos, soaps, toothpastes, shaving creams, hair conditioners, astringents, and antiperspirant/deodorant washes. Allantoin-enriched hair creams and shampoos prevent split ends and breakage; lipsticks and creams with allantoin keep skin and lips soft and elastic.

3. Agricultural Sector: Plant Growth Regulator

Allantoin is an excellent plant growth regulator that stimulates plant growth, significantly increasing yields of wheat, citrus, rice, vegetables, soybeans, and other crops, while promoting fruit setting and early maturation.

4. Other Applications

Oral Care: Added to toothpastes to support oral health.

Biochemical Reagents: Used for content determination, identification, and pharmacological research.