DMDM Hydantoin CAS 6440-58-0 | Bulk Preservative Supplier

1. Scalable Supply & Cost Advantages

As a professional source manufacturer, we own mature hydantoin derivative synthesis production lines, which guarantee stable on-time delivery for large bulk orders and enable us to offer highly competitive ex-factory prices.

2. Strict Quality Control & Global Regulatory Compliance

Our products fully comply with China Cosmetic Safety Technical Specification (2015 Edition) as well as US FDA and EU Cosmetics Regulation (EC) No 1223/2009 requirements. Each batch is accompanied by a complete Certificate of Analysis (COA) covering all critical safety indicators including assay, pH value, total formaldehyde content, free formaldehyde content and heavy metals.

3. Multiple Specifications & Professional Technical Support

Packaging Specifications

Available in various packaging forms: 25kg plastic drums, 50kg plastic drums, 200kg plastic drums and IBC totes.

Product Forms

Multiple forms to choose from: liquid (55% active solution), high-purity powder (≥99% activity).

Grade Options

We offer a comprehensive range of grades including standard hydroxyl grade, suitable hydroxyl grade, anhydrous grade and medium hydroxyl grade (low formaldehyde version). Customized specifications can be provided based on specific customer application requirements.

Application Support

We provide professional formulation optimization suggestions and compounding solutions for different application scenarios (transparent shampoos, conditioners, lotions). For example, compounding with IPBC or parabens to build an efficient broad-spectrum antibacterial system.

1. Cosmetics & Personal Care (Core Application)

DMDM Hydantoin is widely used in cosmetics and personal care products:

Shampoos: Recommended dosage 0.1% - 0.3%, effectively inhibits bacterial growth and extends product shelf life

Conditioners & Hair Masks: Exhibits excellent stability in protein-rich formulations, ensuring product microbial safety

Body Washes & Facial Cleansers: Provides reliable antimicrobial protection in rinse-off formulations

Body Lotions, Creams & Emulsions: Prevents the growth of gram-positive bacteria, gram-negative bacteria and other microorganisms, with excellent inhibitory effect on yeasts and molds

Water-based Color Cosmetics (e.g., liquid foundations): Maintains product microbial stability throughout the shelf life

2. Cross-Industry Industrial Applications

Industrial Coatings & Sealants: Used as an in-can preservative to prevent deterioration of water-based coatings and sealants during storage and transportation, protecting viscosity and physical properties

Adhesives & Elastomer Compounds: Prevents microbial degradation and ensures long-term stability, ideal for systems where conventional biocides have insufficient water solubility

Bactericidal Pesticides: Serves as an active ingredient in various bactericidal pesticide formulations

Q1: What is DMDM Hydantoin?

A: DMDM Hydantoin (INCI Name: DMDM Hydantoin, Trade Name: Glydant, CAS 6440-58-0, EINECS: 229-222-8) is a broad-spectrum antimicrobial formaldehyde-releasing preservative. Its chemical name is 1,3-Dimethylol-5,5-dimethylhydantoin, with a molecular formula of C₇H₁₂N₂O₄ and molecular weight of 188.2 g/mol. The most common commercial form is a 55% aqueous solution that appears as a colorless transparent liquid.

Q2: How does DMDM Hydantoin work as a preservative?

A: DMDM Hydantoin works through a controlled formaldehyde release mechanism. It slowly hydrolyzes in aqueous systems to release trace amounts of free formaldehyde, which disrupts microbial cell membranes and inhibits enzyme activity. This effectively kills and prevents the growth of a wide range of microorganisms including gram-positive bacteria, gram-negative bacteria, yeasts and molds.

Its unique slow-release property ensures long-lasting antimicrobial protection while maintaining low free formaldehyde levels in the final product.

Q3: What is the difference between DMDM Hydantoin and other formaldehyde-releasing preservatives?

A: DMDM Hydantoin offers several key advantages compared to diazolidinyl urea and imidazolidinyl urea:

Lower free formaldehyde content: Typically ≤1% in the raw material, significantly lower than other formaldehyde donors

Better formulation stability: Stable across a wider pH range (4.0-9.0) and compatible with most cosmetic ingredients

Lower skin sensitization risk: Due to its controlled release mechanism and lower free formaldehyde levels

Excellent performance in protein-rich formulations: Does not react with proteins like some other preservatives

Q4: What is the recommended dosage of DMDM Hydantoin?

A: The recommended dosage varies by application:

Shampoos & body washes: 0.1% - 0.3%

Conditioners & hair masks: 0.2% - 0.4%

Creams, lotions & emulsions: 0.3% - 0.6%

Liquid foundations & color cosmetics: 0.2% - 0.5%

Industrial coatings & adhesives: 0.1% - 0.5%

Regulatory limits: Maximum allowed concentration is 0.6% for both rinse-off and leave-on cosmetic products in China, EU and most global markets.

Q5: Is DMDM Hydantoin safe for use in cosmetics?

A: Yes, DMDM Hydantoin has an excellent safety profile when used within recommended concentrations:

CIR Safety Assessment: The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that DMDM Hydantoin is safe for use in cosmetics at concentrations up to 0.6%

Global regulatory approval: Approved by the US FDA, EU Cosmetics Regulation (EC) No 1223/2009 and listed in China's Inventory of Used Cosmetic Ingredients

Low irritation: Has low skin and eye irritation potential and is suitable for most skin types

Q6: What is the formulation compatibility of DMDM Hydantoin?

A: DMDM Hydantoin exhibits excellent formulation compatibility:

pH stability: Stable in formulations with pH 4.0 - 9.0

Processing temperature: Should be added below 50°C to preserve maximum activity

Surfactant compatibility: Fully compatible with anionic, cationic, nonionic and amphoteric surfactants

Synergistic combinations: Works exceptionally well when compounded with IPBC, parabens or phenoxyethanol to create enhanced broad-spectrum preservation systems

Q7: What grades and forms of DMDM Hydantoin do you offer?

A: As a professional source manufacturer, we provide a comprehensive range of products:

Forms: 55% active liquid solution (standard), high-purity powder (≥99% activity)

Grades:

Standard hydroxyl grade (general purpose)

Suitable hydroxyl grade (optimized for transparent formulations)

Anhydrous grade (for water-sensitive systems)

Medium hydroxyl grade (low formaldehyde version)

Custom grades: Available upon request for specific application requirements

Q8: What are the storage and packaging requirements for DMDM Hydantoin?

A:Storage conditions: Store in a cool, dry and well-ventilated place at 5°C - 30°C, away from direct sunlight and heat sources

Shelf life: 24 months from the date of manufacture under proper storage conditions

Standard packaging: 25kg plastic drums, 50kg plastic drums, 200kg plastic drums and 1000L IBC totes

Custom packaging: Available upon request