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Item No :
DetailsOrder(MOQ) :
100kgsProduct Origin :
ChinaColor :
White to off-white (powder/granular grade); Colorless to pale yellow (70% aqueous solution grade)Shipping Port :
Shanghai, ChinaLead Time :
2-3 weeksWeight :
25kgCas No. :
112-02-7Molecular Formula :
C₁₉H₄₂ClNAppearance :
White to off-white free-flowing powder/granules; also available as 70% clear aqueous solutionAssay :
≥ 99.0% (for powder/granular grade); 70% ±1% (for aqueous solution grade)Application :
Widely used as a high-efficiency cationic surfactant, core hair conditioning agent, antistatic agent, thickener and formulation stabilizer in hair care products
Cetrimonium Chloride (INCI Name: Cetrimonium Chloride, CAS 112-02-7) is a high-efficiency cationic surfactant that appears as a white to off-white powder or granules.
As one of the most classic conditioning agents in hair care formulations, it delivers outstanding antistatic performance, exceptional softening and smoothing effects, and significantly improved wet and dry combability of hair. It is widely formulated into a full range of hair care products including hair conditioners, hair masks, shampoos, and hair color creams.
As a professional source manufacturer, we supply high-purity Cetrimonium Chloride with stable and consistent bulk supply capacity for global cosmetic brands and formulators.
Core Advantages
Factory Direct Supply & Competitive Cost Advantage
As a professional source manufacturer of Diazolidinyl Urea, we own a fully in-house production line, which guarantees stable on-time delivery for large bulk orders, while providing highly competitive ex-factory prices for our global partners.
Broad-Spectrum & High-Efficiency Antimicrobial Efficacy
Diazolidinyl Urea delivers excellent broad-spectrum antimicrobial performance, with strong inhibitory effects on Gram-positive bacteria, Gram-negative bacteria (including Pseudomonas species), yeasts and molds, ensuring long-term preservation for various formulations.
Superior Formulation Compatibility
Diazolidinyl Urea has outstanding compatibility with common cosmetic and chemical raw materials. When compounded with parabens, IPBC and other preservatives, it can form a synergistic broad-spectrum antimicrobial system to further enhance overall preservation efficacy.
Full Global Regulatory Compliance
Our Diazolidinyl Urea fully complies with major global cosmetic regulatory standards, including China Cosmetic Safety Technical Specification, EU Cosmetics Regulation (EC 1223/2009), and U.S. FDA cosmetic requirements, fully supporting your product registration and global market access.
Technical Specifications
| Item | Specifications |
| Product Name | Diazolidinyl Urea (Chemical Alias: Bis(hydroxymethyl)imidazolidinyl Urea; Common Trade Names: Germall A, Geiguard II) |
| CAS Number | 78491-02-8 |
| Molecular Formula | C₈H₁₄N₄O₇ |
| Molecular Weight | 278.22 |
| Appearance | White to off-white free-flowing powder, hygroscopic |
| Assay | ≥ 99.0% |
| pH Range | 3 – 9 |
| Solubility | Freely soluble in water, very low oil solubility |
| Main Applications | Creams, lotions, shampoos, hair conditioners, wet wipes, eye cosmetics |
Key Application
1. Cosmetics & Personal Care Products
Diazolidinyl Urea is a high-efficiency broad-spectrum preservative for cosmetic and personal care formulations. It is widely used in leave-on and rinse-off products including creams, lotions, shampoos, hair conditioners, wet wipes and more.
Recommended Dosage: 0.1% – 0.5%
2. Household Cleaning Products
Diazolidinyl Urea effectively inhibits the growth of harmful microorganisms, prevents microbial contamination in household cleaning formulations, significantly extends product shelf life, and maintains long-term stability during storage and daily use.
3. In Vitro Diagnostic (IVD) Reagents
Diazolidinyl Urea serves as a reliable preservative for in vitro diagnostic reagents, suitable for buffer solutions, diluents and cleaning solutions in IVD kits. It is a safe, high-efficiency alternative to sodium azide in diagnostic formulation development.
FAQ: Cetrimonium Chloride
Q1: What is Cetrimonium Chloride?
A: Cetrimonium Chloride (INCI Name: Cetrimonium Chloride, CAS 112-02-7) is a high-efficiency quaternary ammonium cationic surfactant, typically appearing as a white to off-white powder or granules, also available in 70% aqueous solution form. As one of the most classic and widely used hair conditioning agents in the personal care industry, it is a core functional ingredient in hair care and cosmetic formulations worldwide.
Q2: What are the core functions of Cetrimonium Chloride in cosmetic formulations?
A: Cetrimonium Chloride delivers multiple key benefits in formulations, making it a versatile raw material for personal care products:
Superior Hair Conditioning: Adsorbs onto the hair cuticle effectively, significantly improving wet and dry combability, reducing hair breakage, and delivering exceptional softening and smoothing effects.
Outstanding Antistatic Performance: Eliminates static electricity on hair strands, effectively reducing frizz and flyaways, keeping hair smooth and manageable.
Thickening & Stabilizing: Acts as a rheology modifier and formulation stabilizer in surfactant systems, enhancing product viscosity and improving long-term formulation stability.
Auxiliary Emulsifying: Provides certain emulsifying properties in O/W emulsions, supporting the stability of cream and lotion formulations.
Q3: Is Cetrimonium Chloride compatible with other cosmetic ingredients?
A: Cetrimonium Chloride has excellent compatibility with most cosmetic raw materials:
Fully compatible with cationic and non-ionic surfactants, emulsifiers, and conditioning agents, and can be compounded to create synergistic effects (e.g., with Cetearyl Alcohol, Behentrimonium Methosulfate to enhance conditioning performance).
It has limited compatibility with anionic surfactants (e.g., SLES, ALS), as they may form complexes and reduce efficacy; formulation compatibility testing is required when used in combination at low dosages.
It remains stable across a wide pH range (3.0 – 9.0), and is compatible with most active ingredients, preservatives, and oils used in personal care formulations.
Q4: Is Cetrimonium Chloride safe for hair and skin?
A: Yes, Cetrimonium Chloride is a safe cosmetic ingredient when used within the recommended dosage range.
It has been rigorously evaluated and approved for cosmetic use by the CIR (Cosmetic Ingredient Review) Expert Panel, and fully complies with global regulatory standards including EU Cosmetics Regulation (EC 1223/2009), U.S. FDA cosmetic requirements, and China Cosmetic Safety Technical Specification.
At the recommended dosage in rinse-off products (e.g., shampoos, conditioners), it has extremely low skin and scalp irritation, and is suitable for most hair and skin types, including sensitive scalp.
For leave-on products, it is safe to use at dosages ≤ 0.25% in line with global regulatory limits.
Q5: Does Cetrimonium Chloride cause hair build-up or damage?
A: When used at the recommended dosage, Cetrimonium Chloride will not cause harmful hair build-up or damage.
It adsorbs onto the hair cuticle in a uniform, thin layer, filling gaps in damaged cuticles to protect hair, rather than accumulating in heavy, stiff layers.
The so-called "build-up" is usually caused by excessive dosage or improper formulation compounding, not the ingredient itself. For daily use, rinse-off products with standard dosages will not cause build-up, and can effectively improve hair health and manageability.
Q6: What specifications of Cetrimonium Chloride do you offer?
A: As a professional source manufacturer, we provide customizable specifications to meet diverse formulation and production needs:
Active Content Grades: 99% high-purity powder/granules, 70% aqueous solution
Packaging Specifications: 20kg bags, 25kg fiber drums, and customizable packaging options
Compliance Support: Full technical documentation including Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and regulatory compliance files to support global market access.
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