Cosmetic Grade Methyl Paraben for Skincare & Personal Care | CAS 99-76-3

• Methyl Paraben (also written as Methylparaben, CAS 99-76-3) is a broad spectrum antimicrobial preservative, appearing as a white crystalline powder.
  
  
• It effectively inhibits the growth of bacteria, yeast and mold. With its high efficacy, proven safety and cost-effective performance, it is widely used in cosmetics, food and pharmaceutical industries.
  
  
• As a direct source manufacturer, we supply high-purity methyl paraben products with guaranteed stable bulk supply capacity.

1. Direct Source Factory Supply

Guaranteed stable bulk delivery with highly competitive ex-factory prices for premium methyl paraben.

2. Broad Spectrum High-Efficacy Antimicrobial Activity

Delivers strong inhibitory effect against bacteria, yeast and mold, with reliable and stable preservative performance.

3. Long Proven Application History

Decades of proven safe use in the food, cosmetic and pharmaceutical industries globally.

4. Flexible Formulation Compatibility

Can be used alone, or blended with other paraben esters (ethyl paraben, propyl paraben) for synergistic preservative effect.

5. Full Global Regulatory Compliance

Cosmetics: Compliant with China Cosmetic Safety Technical Specification and EU Cosmetics Regulation (EC) No 1223/2009

Food: Listed as FDA GRAS (Generally Recognized As Safe) substance, maximum addition limit 0.1% in food products 

1. Cosmetics & Personal Care Products

Widely used as a preservative in creams, lotions, shampoos, color cosmetics and other personal care products. Suitable for both leave-on and rinse-off formulations.

2. Food & Beverage

Used as a food preservative to effectively prevent microbial growth. In the United States, it is recognized as GRAS (Generally Recognized As Safe) for use as a food preservative.

3. Pharmaceutical & Medicinal Products

Used as an antiseptic preservative for pharmaceuticals, oral liquids and topical preparations.

Q1: What is Methyl Paraben, and what are its common names?

A: Methyl Paraben (also written as Methylparaben, chemical name: Methyl p-Hydroxybenzoate, CAS 99-76-3) is the methyl ester derivative of p-hydroxybenzoic acid. It appears as a white crystalline powder, odorless or almost odorless. Common trade names include Nipagin M. It is one of the most widely used broad spectrum preservatives globally.

Q2: What is the antimicrobial spectrum of Methyl Paraben?

A: Methyl Paraben delivers broad spectrum antimicrobial activity: it effectively inhibits the growth of bacteria, yeast and mold, with particularly high efficacy against fungi (yeast and mold). It is widely recognized for its stable and reliable preservative performance across a wide pH range.

Q3: What is the recommended usage level of Methyl Paraben in different formulations?

A: The standard recommended dosage:

Cosmetics: 0.03% – 0.30% for optimal preservative efficacy

Regulatory limit (EU & China): Maximum 0.4% when used alone; maximum 0.8% total parabens when blended with other paraben esters

Food: Maximum 0.1% (1 mg/g) per FDA GRAS standard

Q4: Is Methyl Paraben compliant with global regulatory standards?

A: Yes, Methyl Paraben has full global regulatory approval:

Cosmetics: Compliant with China Cosmetic Safety Technical Specification and EU Cosmetics Regulation (EC) No 1223/2009

Food: US FDA GRAS (Generally Recognized As Safe), approved for use as food preservative

Pharmaceutical: Compliant with USP, NF, Ph. Eur. pharmacopoeia standards

Q5: Is Methyl Paraben safe for use, and is it carcinogenic?

A: Yes, high-purity Methyl Paraben has an excellent safety profile when used within regulatory concentration limits. Extensive scientific research and decades of global safe use confirm:

It has no carcinogenic potential at approved usage levels

It has low sensitization potential and is suitable for most formulation types

All major global regulatory bodies (FDA, EU SCCS, WHO) confirm its safety for approved uses

Q6: Can Methyl Paraben be combined with other preservatives for synergistic effect?

A: Yes, Methyl Paraben has excellent formulation compatibility. It delivers significant synergistic preservative effect when blended with other paraben esters (ethyl paraben, propyl paraben, butyl paraben), expanding antimicrobial spectrum and reducing total required concentration. It also works well with most other cosmetic and food preservatives.

Q7: In which products and industries is Methyl Paraben commonly applied?

A: Methyl Paraben is widely used across 3 major industries:

Cosmetics & personal care: Creams, lotions, serums, makeup, hair care, oral care products; suitable for both leave-on and rinse-off formulations

Food & beverage: Beverages, processed foods, syrups, pickled products

Pharmaceutical: Oral liquids, topical preparations, injections and other medicinal products

Q8: What are the key quality specifications for premium Methyl Paraben?

A: High-quality cosmetic/food/pharmaceutical grade Methyl Paraben meets the following core specifications:

Purity: ≥ 99.0%

Melting point: 125 – 128°C

Appearance: White crystalline powder or colorless crystals

Solubility: Slightly soluble in water (1g/400ml), freely soluble in ethanol

Q9: Is Methyl Paraben stable in formulations?

A: Yes, Methyl Paraben has excellent chemical stability: it is non-volatile, chemically inert, and maintains full preservative efficacy under conventional storage and processing conditions across a wide pH range (4-8). It is one of the most stable preservatives available.

Q10: Does Methyl Paraben cause skin irritation or sensitization?

A: High-purity Methyl Paraben has very low sensitization potential when used within recommended concentrations. It is suitable for a wide range of formulations including most sensitive skin products, and has a decades-long history of safe use in personal care products.

Q11: Is Methyl Paraben water soluble?

A: Methyl Paraben is slightly soluble in water (approximately 1g per 400ml water at room temperature), and freely soluble in ethanol, ether and other organic solvents. It can be easily incorporated into both water-based and oil-based formulations.