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Epimedium Icariin Extract Standardized 50%-98% Purity Food/Pharma Grade | CAS 489-32-7
Item No :
LEAFCHEM053Order(MOQ) :
100kgsProduct Origin :
ChinaColor :
White to pale yellowShipping Port :
Shanghai, ChinaLead Time :
2-3 weeksWeight :
25kgCas No. :
489-32-7Molecular Formula :
C₃₃H₄₀O₁₅Appearance :
White to pale yellow fine powder, odorless or almost odorless, good fluidity, no cakingAssay :
Icariin: 50%, 80%, 90%, 98% (standard) available, customizable purity from 10% to 98% (tested by HPLC)Application :
Bone health products Men’s health supplements Sports nutrition products Pharmaceutical R&D Scientific research
Core Advantages
Technical Specifications
| ltem | Specification (Example) | Test Method |
| Appearance | White to pale yellow fine powder | Visual inspection |
| Content (Key Index) | Icariin: 50%,80%,90%,98% (HPLC),etc.(Customizable) | High Performance Liquid Chromatography (HPLC) |
| Loss on Drying | ≤ 5.0% | Loss on Drying Method at 105°C |
| Residue on lgnition | ≤ 1.0% | General Principles of the Chinese Pharmacopoeia |
| Heavy Metals | Lead (Pb) ≤ 2 mg/kg; Total Heavy Metals ≤ 10 mg/kg | ICP-MS/Atomic Absorption Spectroscopy (AAS) |
| Solvent Residues | Compliant with lCH guidelines or customer requirements(e.g., ethanol, ethyl acetate) | Gas Chromatography (GC) |
Key Application Fields
Bone Health Products
Core Application : Serves as a core raw material in health food or Food for Special Medical Purposes (FSMP) for preventing and ameliorating osteoporosis, increasing bone mineral density and accelerating fracture healing. It features a well-defined mechanism of action in boosting osteoblast activity.
Men’s Health & Sports Nutrition
Used in men’s health supplements to enhance sexual function and boost physical vitality.
Incorporated into sports nutrition products for improving endurance, combating fatigue and facilitating post-exercise physical recovery.
High-End Pharmaceutical & Botanical Drug R&D
Acts as an active pharmaceutical ingredient (API) or intermediate for the R&D of modernized traditional Chinese medicine products, innovative botanical drugs and prescription drugs with well-characterized active components.
Other Research Fields
Its applications in neuroprotection, cardiovascular health and antidepressant effects are also under active research.
FAQ ：Icariin Extract
Q: What is Icariin Extract, and how is it different from conventional Epimedium extract?
A: Icariin Extract is a standardized high-purity monomeric botanical ingredient refined from Epimedium via modern separation and purification technologies (e.g., macroporous resin adsorption, column chromatography). Its core active component is icariin (CAS 489-32-7), a single defined compound with a clear molecular formula (C₃₃H₄₀O₁₅). Unlike conventional crude Epimedium extract (a mixed component product with low icariin content), it features defined composition, clear action mechanism and significantly higher biological activity, and is a targeted raw material for high-end product development.
Q: What are the core biological activities and action mechanisms of Icariin Extract?
A: Its core biological activities are backed by scientific research, with clear and verifiable mechanisms:
Bone health support: Promotes osteoblast proliferation and activity, inhibits osteoclast formation, effectively increases bone mineral density and ameliorates osteoporosis;
Physical vitality enhancement: Regulates related signaling pathways to improve sexual function and relieve physical fatigue;
Athletic performance improvement: Enhances the body’s anti-fatigue capacity, accelerates post-exercise energy recovery and improves exercise endurance.
In addition, its potential activities in neuroprotection, cardiovascular health and antidepressant effects are under active research.
Q: Why is high-purity icariin more advantageous for product R&D than low-purity variants?
A: High-purity icariin (≥90%, especially 98%) has three core R&D advantages:
Accurate dose control: The single active component ensures precise calculation of the effective dose in end products, avoiding dose uncertainty caused by mixed components;
Reliable efficacy claims: The clear action mechanism and scientific research data provide a solid basis for compliant efficacy claims of health food and pharmaceutical products;
Superior R&D compatibility: It is more suitable for advanced formulation development (e.g., nanoparticulate formulations, targeted delivery systems) and in-depth pharmacokinetic studies, which is difficult to achieve with low-purity mixed extracts.
Q: What purity specifications of Icariin Extract do you provide, and can they be customized?
A: We offer food grade, health grade and pharmaceutical grade Icariin Extract with full-range customizable purity for different application scenarios:
Standard specifications: 50%, 80%, 90% icariin (cost-effective for health food and sports nutrition products);
High-purity specifications: 98% icariin (pharmaceutical grade, for bone health high-end supplements and pharmaceutical R&D);
Customizable specifications: Any purity range from 10% to 98% icariin can be customized according to customer R&D and production needs.
Q: Can you provide water-soluble Icariin Extract for beverage and oral liquid formulations?
A: Yes. Our standard icariin extract is slightly soluble in water, and we can customize highly water-soluble Icariin Extract via special molecular modification and formulation technology. The water-soluble variant has good water dispersibility, no precipitation, stable activity, and is suitable for clear functional beverages, oral liquids and solid beverage formulations with strict solubility requirements.
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