Leave A Message
If you are interested in our products and want to know more details,please leave a message here,we will reply you as soon as we can.
Epimedium Icariin Extract Standardized 50%-98% Purity Food/Pharma Grade | CAS 489-32-7
Icariin Extract is a professional botanical raw material highly enriched in Icariin—the core active monomer (CAS 489-32-7). It presents as a white to pale yellow powder with a customizable purity range of 10% to 98%, featuring a defined composition and clear action mechanism. Its core efficacy focuses on promoting bone formation, ameliorating osteoporosis, boosting physical vitality and combating fatigue, making it the premier potent, standardized raw material for developing high-end bone health, men’s wellness and sports nutrition products.
Item No :
LEAFCHEM053Order(MOQ) :
100kgsProduct Origin :
ChinaColor :
White to pale yellowShipping Port :
Shanghai, ChinaLead Time :
2-3 weeksWeight :
25kgCas No. :
489-32-7Molecular Formula :
C₃₃H₄₀O₁₅Appearance :
White to pale yellow fine powder, odorless or almost odorless, good fluidity, no cakingAssay :
Icariin: 50%, 80%, 90%, 98% (standard) available, customizable purity from 10% to 98% (tested by HPLC)Application :
Bone health products Men’s health supplements Sports nutrition products Pharmaceutical R&D Scientific research
Core Advantages
Technical Specifications
| ltem | Specification (Example) | Test Method |
| Appearance | White to pale yellow fine powder | Visual inspection |
| Content (Key Index) | Icariin: 50%,80%,90%,98% (HPLC),etc.(Customizable) | High Performance Liquid Chromatography (HPLC) |
| Loss on Drying | ≤ 5.0% | Loss on Drying Method at 105°C |
| Residue on lgnition | ≤ 1.0% | General Principles of the Chinese Pharmacopoeia |
| Heavy Metals | Lead (Pb) ≤ 2 mg/kg; Total Heavy Metals ≤ 10 mg/kg | ICP-MS/Atomic Absorption Spectroscopy (AAS) |
| Solvent Residues | Compliant with lCH guidelines or customer requirements(e.g., ethanol, ethyl acetate) | Gas Chromatography (GC) |
Key Application Fields
Bone Health Products
Core Application : Serves as a core raw material in health food or Food for Special Medical Purposes (FSMP) for preventing and ameliorating osteoporosis, increasing bone mineral density and accelerating fracture healing. It features a well-defined mechanism of action in boosting osteoblast activity.
Men’s Health & Sports Nutrition
Used in men’s health supplements to enhance sexual function and boost physical vitality.
Incorporated into sports nutrition products for improving endurance, combating fatigue and facilitating post-exercise physical recovery.
High-End Pharmaceutical & Botanical Drug R&D
Acts as an active pharmaceutical ingredient (API) or intermediate for the R&D of modernized traditional Chinese medicine products, innovative botanical drugs and prescription drugs with well-characterized active components.
Other Research Fields
Its applications in neuroprotection, cardiovascular health and antidepressant effects are also under active research.
FAQ ：Icariin Extract
Q: What is Icariin Extract, and how is it different from conventional Epimedium extract?
A: Icariin Extract is a standardized high-purity monomeric botanical ingredient refined from Epimedium via modern separation and purification technologies (e.g., macroporous resin adsorption, column chromatography). Its core active component is icariin (CAS 489-32-7), a single defined compound with a clear molecular formula (C₃₃H₄₀O₁₅). Unlike conventional crude Epimedium extract (a mixed component product with low icariin content), it features defined composition, clear action mechanism and significantly higher biological activity, and is a targeted raw material for high-end product development.
Q: What are the core biological activities and action mechanisms of Icariin Extract?
A: Its core biological activities are backed by scientific research, with clear and verifiable mechanisms:
Bone health support: Promotes osteoblast proliferation and activity, inhibits osteoclast formation, effectively increases bone mineral density and ameliorates osteoporosis;
Physical vitality enhancement: Regulates related signaling pathways to improve sexual function and relieve physical fatigue;
Athletic performance improvement: Enhances the body’s anti-fatigue capacity, accelerates post-exercise energy recovery and improves exercise endurance.
In addition, its potential activities in neuroprotection, cardiovascular health and antidepressant effects are under active research.
Q: Why is high-purity icariin more advantageous for product R&D than low-purity variants?
A: High-purity icariin (≥90%, especially 98%) has three core R&D advantages:
Accurate dose control: The single active component ensures precise calculation of the effective dose in end products, avoiding dose uncertainty caused by mixed components;
Reliable efficacy claims: The clear action mechanism and scientific research data provide a solid basis for compliant efficacy claims of health food and pharmaceutical products;
Superior R&D compatibility: It is more suitable for advanced formulation development (e.g., nanoparticulate formulations, targeted delivery systems) and in-depth pharmacokinetic studies, which is difficult to achieve with low-purity mixed extracts.
Q: What purity specifications of Icariin Extract do you provide, and can they be customized?
A: We offer food grade, health grade and pharmaceutical grade Icariin Extract with full-range customizable purity for different application scenarios:
Standard specifications: 50%, 80%, 90% icariin (cost-effective for health food and sports nutrition products);
High-purity specifications: 98% icariin (pharmaceutical grade, for bone health high-end supplements and pharmaceutical R&D);
Customizable specifications: Any purity range from 10% to 98% icariin can be customized according to customer R&D and production needs.
Q: Can you provide water-soluble Icariin Extract for beverage and oral liquid formulations?
A: Yes. Our standard icariin extract is slightly soluble in water, and we can customize highly water-soluble Icariin Extract via special molecular modification and formulation technology. The water-soluble variant has good water dispersibility, no precipitation, stable activity, and is suitable for clear functional beverages, oral liquids and solid beverage formulations with strict solubility requirements.
leave a message
IPv6 network supported