Methyl Salicylate COX inhibitor analgesic mechanism

Methyl Salicylate (common name: Wintergreen Oil, CAS 119-36-8) is a naturally occurring organic ester compound, appearing as a colorless to pale yellow oily liquid with characteristic wintergreen leaf aroma. As the core active ingredient of topical analgesics, it exerts anti-inflammatory and analgesic effects by inhibiting cyclooxygenase (COX). It is also a classic flavor and fragrance raw material widely used in toothpaste, mouthwash, chewing gum, candies and beverages.